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Author Jae Gu Jung, Hyoun Woo Kang, Suk Jae Hahn, Jong Sun Choi1 and Eung Joong Kim2
Place of duty Departments of Internal Medicine, Pathology1, and Thoracic and Cardiovascular Surgery2, Dongguk University Ilsan Hospital, Goyang, Korea
Title Primary Mucosa-associated Lymphoid Tissue Lymphoma of the Esophagus, Manifesting as a Submucosal Tumor
Publicationinfo The Korean Journal of Gastroenterology 2013 Aug; 062(02): 117-121.
Key_word Esophagus; Lymphoma; B-Lymphocytes; Marginal zone B-cell lymphoma
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Abstract Background/Aims: Benign biliary strictures (BBSs) have been endoscopically managed with plastic stent placement. However, data regarding fully covered self-expandable metal stents (FCSEMSs) in BBS patients remain scarce in Korea. Methods: We report a case of primary mucosa-associated lymphoid tissue (MALT) lymphoma in the esophagus that manifested as a large submucosal tumor (SMT). Primary esophageal lymphoma is very rare, occurring in less than 1% of all patients with gastrointestinal lymphoma. Only a few cases of MALT lymphoma in the esophagus have been reported in the English literature. A 53-year-old man was referred to Dongguk University Ilsan Hospital (Goyang, Korea) in July 2012 for further evaluation and treatment of an esophageal SMT. Endoscopy showed a cylindrically elongated submucosal mass with normal overlying mucosa in the mid esophagus, 25-30 cm from the incisor teeth. He underwent surgery to confirm the diagnosis. Pathologic findings showed diffuse small atypical lymphoid cells which were stained with Bcl-2, CD20, but not with CD3, CD5, CD23, Bcl-6, or cyclin D1. These cells showed a positive monoclonal band for immunoglobulin heavy chain gene rearrangement. Based on the pathological, immunohistochemical, and molecular biological features, the esophageal mass was diagnosed as extranodal marginal zone B-cell lymphoma of the MALT type. (Korean J Gastroenterol 2013;62:117-121)
저 자 정재규, 강현우, 한석재, 최종순1, 김응중2
소 속 동국대학교 일산병원 내과, 병리학과1, 흉부외과2
제 목 점막하 종양으로 발현한 원발성 식도 점막 연관 림프조직 림프종 1예
출판정보 Korean J Gastroenterol 2013 Aug; 062(02): 117-121.
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