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Author Yeon-Joo Kim, Hyun-Soo Kim, Seon-Young Park, Sang-Woo Park, Yoo-Duk Choi1, Chang-Hwan Park, Sung-Kyu Choi and Jong-Sun Rew
Place of duty Departments of Internal Medicine and Pathology1, Chonnam National University Medical School, Gwangju, Korea
Title Intestinal Amyloidosis with Intractable Diarrhea and Intestinal Pseudo-obstruction
Publicationinfo The Korean Journal of Gastroenterology 2012 Sep; 060(03): 172-176.
Key_word Amyloidosis; Diarrhea; Intestinal pseudo-obstruction
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Abstract We report herein a case of intestinal amyloidosis with grave prognosis that caused intractable diarrhea and intestinal pseudo-obstruction, alternately in spite of intensive conservative treatment. A 44-year-old woman was admitted for fever, diarrhea, and crampy abdominal pain which had been continuned during 6 months. Abdomen CT scan showed edematous wall thickening of the small bowel and right colon, and colonoscopic biopsy revealed amyloid deposition in the mucosa. Monoclonal light chains in serum and/or urine were not detected and highly elevated serum amyloid A was shown. In spite of intensive treatment including oral prednisolone and colchicine, diarrhea and intestinal pseudo-obstruction developed alternately, general status rapidly got worsened and died after two months. (Korean J Gastroenterol 2012;60:172-176)
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